In Europe, >33,000 organ transplants are performed every year and >500 are performed in Spain. This population is especially vulnerable to respiratory viral infections. Very scarce information is available regarding the clinical manifestations, epidemiological and outcome of solid organ transplant recipients (SOTR) with COVID-19 exist. Nevertheless, given the behavior of non-epidemic coronavirus in immunosuppressed patients, a higher number of COVID-19 complications in this population could be expected with an important impact on morbidity and mortality in SOTR, especially in the very early post-transplant period (as observed with influenza).

The overall purpose of this project is to better understand the incidence, risk factors, etiology, clinical manifestations and outcome of COVID-19 in SOTR. The results obtained will allow us to gain insight on the need of antiviral treatment, on the strategy for complications surveillance, on how to adjust the immunosuppressive therapy and on the level of care in which each patient should be treated.

In order to attain the objectives previously described we will develop the following studies:

  • An international multicenter retrospective study of cases of COVID-19 among SOTR. Only retrospective clinical data will be included in this registry and no informed consent will be needed.
  • An international multicenter prospective study of SOTR with COVID-19 diagnosis.

For the setup of the studies with such characteristics, a coordinated and normalized information network becomes crucial to offer very fast good quality information. This study is part of an initiative of Spanish Network for the Research in Infectious Diseases (REIPI) and the GESITRA-IC group of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).

If you are interested in participating in any (or both) studies please contact with